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1

A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7

Wang, Wesley Wei, Angulo-Ibanez, Maria, Lyu, Jie, Kurra, Yadagiri, Tong, Zhen, Wu, Bo, Zhang, Ling, Sharma, Vangmayee, Zhou, Jennifer, Lin, Hening, Gao, Yi Qin, Li, Wei, Chua, Katrin F., Liu, Wenshe R

Journal:

Journal of the American Chemical Society

Année:

2019

Fichier:

PDF, 2 KB

2019

2

10.1038/46092

Reed, Robin, Chua, Katrin

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 100 KB

english, 1999

3

10.1038/46086

Reed, Robin, Chua, Katrin

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 205 KB

english, 1999

4

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raul Mostoslavsky, Katrin F. Chua, David B. Lombard, Wendy W. Pang, Miriam R. Fischer, Lionel Gellon, Pingfang Liu, Gustavo Mostoslavsky, Sonia Franco, Michael M. Murphy, Kevin D. Mills, Parin Patel,

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 977 KB

english, 2006

5

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Chaudhuri, Jayanta, Tian, Ming, Khuong, Chan, Chua, Katrin, Pinaud, Eric, Alt, Frederick W.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 347 KB

english, 2003

6

The influence of transcriptional orientation on endogenous switch region function

Shinkura, Reiko, Tian, Ming, Smith, Michele, Chua, Katrin, Fujiwara, Yuko, Alt, Frederick W.

Journal:

Nature Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 627 KB

english, 2003

7

Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization

Ruth I. Tennen, Elisabeth Berber, Katrin F. Chua

Journal:

Mechanisms of Ageing and Development

Année:

2010

Langue:

english

Fichier:

PDF, 466 KB

english, 2010

8

Chromatin regulation and genome maintenance by mammalian SIRT6

Ruth I. Tennen, Katrin F. Chua

Journal:

Trends in Biochemical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 373 KB

english, 2011

9

Finding a Target for Resveratrol

Ruth I. Tennen, Eriko Michishita-Kioi, Katrin F. Chua

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 224 KB

english, 2012

10

DNA Repair, Genome Stability, and Aging

David B. Lombard, Katrin F. Chua, Raul Mostoslavsky, Sonia Franco, Monica Gostissa, Frederick W. Alt

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 427 KB

english, 2005

11

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

Tiara L.A. Kawahara, Eriko Michishita, Adam S. Adler, Mara Damian, Elisabeth Berber, Meihong Lin, Ron A. McCord, Kristine C.L. Ongaigui, Lisa D. Boxer, Howard Y. Chang, Katrin F. Chua

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2009

12

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

Katrin F. Chua, Raul Mostoslavsky, David B. Lombard, Wendy W. Pang, Shin’ichi Saito, Sonia Franco, Dhruv Kaushal, Hwei-Ling Cheng, Miriam R. Fischer, Nicole Stokes, Michael M. Murphy, Ettore Appella,

Journal:

Cell Metabolism

Année:

2005

Langue:

english

Fichier:

PDF, 490 KB

english, 2005

13

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

Katrin F. Chua, Raul Mostoslavsky, David B. Lombard, Wendy W. Pang, Shin'ichi Saito, Sonia Franco, Dhruv Kaushal, Hwei-Ling Cheng, Miriam Fischer, Nicole Stokes, Michael M. Murphy, Ettore Appella, Fre

Journal:

Cell Metabolism

Année:

2006

Langue:

english

Fichier:

PDF, 30 KB

english, 2006

14

The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC

J.Andrew Berglund, Katrin Chua, Nadja Abovich, Robin Reed, Michael Rosbash

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 160 KB

english, 1997

15

Histone H2AX: A Dosage-Dependent Suppressor of Oncogenic Translocations and Tumors

Craig H. Bassing, Heikyung Suh, David O. Ferguson, Katrin F. Chua, John Manis, Mark Eckersdorff, Megan Gleason, Rodrick Bronson, Charles Lee, Frederick W. Alt

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 534 KB

english, 2003

16

Cancer: Metabolism in 'the driver's seat

Tasselli, Luisa, Chua, Katrin F.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 260 KB

english, 2012

17

A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation

Moore, Kaitlyn E., Carlson, Scott M., Camp, Nathan D., Cheung, Peggie, James, Richard G., Chua, Katrin F., Wolf-Yadlin, Alejandro, Gozani, Or

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2013

18

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling

Simeoni, Federica, Tasselli, Luisa, Tanaka, Shinji, Villanova, Lidia, Hayashi, Mayumi, Kubota, Kazuishi, Isono, Fujio, Garcia, Benjamin A., Michishita-Kioi, Eriko, Chua, Katrin F.

Journal:

Scientific Reports

Année:

2013

Langue:

english

Fichier:

PDF, 1019 KB

english, 2013

19

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6

Michishita, Eriko, McCord, Ronald A., Boxer, Lisa D., Barber, Matthew F., Hong, Tao, Gozani, Or, Chua, Katrin F.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 701 KB

english, 2009

20

SIRT6 is required for maintenance of telomere position effect in human cells

Tennen, Ruth I., Bua, Dennis J., Wright, Woodring E., Chua, Katrin F.

Journal:

Nature Communications

Année:

2011

Langue:

english

Fichier:

PDF, 626 KB

english, 2011

21

Methylation gets into rhythm with NAD+-SIRT1

Tasselli, Luisa, Chua, Katrin F

Journal:

Nature Structural and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 540 KB

english, 2015

22

Nuclear DNA damage signalling to mitochondria in ageing

Fang, Evandro Fei, Scheibye-Knudsen, Morten, Chua, Katrin F., Mattson, Mark P., Croteau, Deborah L., Bohr, Vilhelm A.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2016

Langue:

english

Fichier:

PDF, 706 KB

english, 2016

23

SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence

Tasselli, Luisa, Xi, Yuanxin, Zheng, Wei, Tennen, Ruth I, Odrowaz, Zaneta, Simeoni, Federica, Li, Wei, Chua, Katrin F

Journal:

Nature Structural and Molecular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2016

24

Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells

Seghezzi, Wolfgang, Chua, Katrin, Shanahan, Frances, Gozani, Or, Reed, Robin, Lees, Emma

Journal:

Molecular and Cellular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1998

25

SIRT6: Novel Mechanisms and Links to Aging and Disease

Tasselli, Luisa, Zheng, Wei, Chua, Katrin F.

Journal:

Trends in Endocrinology & Metabolism

Année:

2016

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2016

26

SIRT7 clears the way for DNA repair

Paredes, Silvana, Chua, Katrin F

Journal:

The EMBO Journal

Année:

2016

Langue:

english

Fichier:

PDF, 315 KB

english, 2016

27

Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

You, Weijie, Rotili, Dante, Li, Tie-Mei, Kambach, Christian, Meleshin, Marat, Schutkowski, Mike, Chua, Katrin F., Mai, Antonello, Steegborn, Clemens

Journal:

Angewandte Chemie International Edition

Année:

2017

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2017

28

Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

You, Weijie, Rotili, Dante, Li, Tie-Mei, Kambach, Christian, Meleshin, Marat, Schutkowski, Mike, Chua, Katrin F., Mai, Antonello, Steegborn, Clemens

Journal:

Angewandte Chemie

Année:

2017

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2017

29

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

Malik, Shivani, Villanova, Lidia, Tanaka, Shinji, Aonuma, Misato, Roy, Nilotpal, Berber, Elisabeth, Pollack, Jonathan R., Michishita-Kioi, Eriko, Chua, Katrin F.

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 4.46 MB

english, 2015

30

The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability

Paredes, Silvana, Angulo-Ibanez, Maria, Tasselli, Luisa, Carlson, Scott M., Zheng, Wei, Li, Tie-Mei, Chua, Katrin F.

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 14.88 MB

english, 2018

31

Regulation of Cullin RING E3 Ubiquitin Ligases by CAND1 In Vivo

Chua, Yee Shin, Boh, Boon Kim, Ponyeam, Wanpen, Hagen, Thilo, Bielinsky, Anja-Katrin

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2011

32

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

McCord, Ronald A., Michishita, Eriko, Hong, Tao, Berber, Elisabeth, Boxer, Lisa D., Kusumoto, Rika, Guan, Shenheng, Shi, Xiaobing, Gozani, Or, Burlingame, Alma L., Bohr, Vilhelm A., Chua, Katrin F.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 974 KB

english, 2009

33

P2-228 [Encore]Randomised Phase 3 Study of Regorafenib in Refractory Advanced Gastro-Oesophageal Cancer (AGOC) - INTEGRATE II

Chua, Yu Jo, Pavlakis, Nick, Sjoquist, Katrin M, Martin, Andrew J, Tsobanis, Eric, Yip, Sonia, Bang, Yung-Jue, Alcindor, Thierry, O’callaghan, Christopher J, Bekaii-Saab, Tanios S, Grothey, Axel, Chen

Journal:

Annals of Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 79 KB

english, 2019

34

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules

Li, Tie-Mei, Coan, John P., Krajewski, Krzysztof, Zhang, Lichao, Elias, Joshua E., Strahl, Brian D., Gozani, Or, Chua, Katrin F.

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 7.14 MB

2019

35

Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives

You, Weijie, Zheng, Wei, Weiss, Sandra, Chua, Katrin F., Steegborn, Clemens

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 1.97 MB

2019

36

Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient Î²-catenin degradation

Li, Tie-Mei, Ren, Jing, Husmann, Dylan, Coan, John P., Gozani, Or, Chua, Katrin F.

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 4.09 MB

2020